The escalating volume and intricate nature of healthcare and social care datasets necessitate the implementation of unconventional feature learning strategies to tackle current challenges. The examination of health and ...
Healthcare has been undergoing a data-driven transformation, further accelerated by the COVID-19 pandemic. A significant amount of healthcare data is unstructured and underutilized. The success of Large Language Models ...
Blood cancer has emerged as a growing concern over the past decade, necessitating early detection for timely and effective treatment. Traditional methods of diagnosing blood cancers involve a series of pathological tests ...
Cancer has become the second leading cause of mortality worldwide, and early de-tection and adequate treatment are crucial in reducing the cancer burden. Metastasis,which involves malignant cells detaching from the primary ...
Circadian rhythms (CR) are 24h endogenous oscillations seen in all organisms that control different biological processes including sleep-wake cycles, body temperature, cell division cycle, heartbeat, and metabolic rates. ...
Omic signatures of disease are important for personalized treatment because of theheterogeneity of diseases. Despite the advancement of computational tools, there arelimited methods that can capture the latent inter-relationships ...
Social determinants of health (SDOH) are the non-medical factors that play a vital role in public health and form the basis of health policies. Building an effective public health policy is a complex endeavor that ...
The advent of tissue and single cell based transcriptomic profiling technologies has allowed precise characterization of tissue specific gene activities in the context of development and disease. Human cells express about ...
For effective treatment regimens, decisions should be based on specific genetic variability present across different human body cells by taking advantage of already accessible large-scale omics data like genomics, epigenomics, ...
Single-cell transcriptomics is a powerful technique that has revolutionized our approach to dissect cellular phenotypes and diversity in complex tissues at an unprecedented res- olution. The emergence of this groundbreaking ...
Kaur, Dilraj; Raghava, Gajendra Pal Singh (Advisor)(IIIT-Delhi, 2022-06)
Innate immune system response is the initial/first line of defense against invading pathogens. It is non-specific and involves various cells like macrophages, neutrophils, natural killer cells, dendritic cells. The response ...
Lathwal, Anjali; Raghava, Gajendra Pal Singh (Advisor)(IIIT-Delhi, 2020-09)
According to the World Health Organization report, around 10 million new cases are diagnosed with cancer in the year 2018 alone. Out of these, nearly 45% of the cancer incidences were reported from the Asian countries, 26% ...
Sharma, Neelam; Raghava, Gajendra Pal Singh (Advisor)(IIIT-Delhi, 2022-06)
Microbes are minute, unicellular, multicellular organisms, such as bacteria, algae, fungi, viruses and protozoans, that can be only visible through the microscope. These can be infectious as well as non-infectious in nature. ...
Patiyal, Sumeet; Raghava, Gajendra Pal Singh (Advisor)(IIIT-Delhi, 2022-08)
Proteins play major roles in many biological processes such as enzymes, transporters, replication, transcription, gene expression regulation, repair and building of tissues, energy production, molecule transport, muscle ...
Dhall, Anjali; Raghava, Gajendra Pal Singh (Advisor)(IIIT-Delhi, 2022-10)
One of the major challenges in designing the cancer vaccine or immunotherapy is to predict the cancer-specific peptides or neopeptides that can stimulate the immune system to fight against the cancer cells. Human leukocyte ...
Arora, Chakit; Raghava, Gajendra Pal Singh (Advisor)(IIIT-Delhi, 2021-08)
With about 19 million occurrences and 10 million mortalities in 2020, “Cancer” is the second leading source of mortality worldwide (WHO GLOBOCAN). The top three continents burdened with cancer deaths are Asia (58.3 percent), ...