Abstract:
This project involves the identification of miRNAs that are differentially expressed across Indolent Vs Progressive and Case Vs Control samples in Chronic Lymphocytic Leukemia (CLL). For
this, we have analysed miRNA sequence data files and RT-PCR data on Chronic Lymphocyitc
Leukemia (CLL) which were provided by AIIMS. The pathways associated with the differentially expressed miRs have also been identified. The implementation involves the utilisation
of mirDeep*, R, CD-HIT,WEKA, miRNet and miRCarta for analysis. Python and Bash shell
scripting were also used during the feature extraction process.
