Arora, Chakit; Raghava, Gajendra Pal Singh (Advisor)(IIIT-Delhi, 2021-08)
With about 19 million occurrences and 10 million mortalities in 2020, “Cancer” is the second leading source of mortality worldwide (WHO GLOBOCAN). The top three continents burdened with cancer deaths are Asia (58.3 percent), ...
Text classification is a construction problem of models which can classify new documents into predefined classes. It is important before text mining that we know what is the most important data that we require for our ...
Walia, Anjali; Raghava, Gajendra Pal Singh (Advisor)(IIIT-Delhi, 2020-07)
LeukemiaBD, is a Database of Biomarker data for Leukemia. The aim of this database is to serve
as a comprehensive repository catering to all relevant information related to Leukemia. The
database currently has manually ...
Genetics has brought huge breakthroughs in understanding human health & wellbeing, diseases and treatment through modern methods such as personalized medicine. This has been possible through substantial research in the ...
Metabolomics, defined as the study of an organism’s entire metabolic profile, is a direct read-out of the physiological changes at the cellular level and has the potential to positively inform drug-target discovery and ...
Lathwal, Anjali; Raghava, Gajendra Pal Singh (Advisor)(IIIT-Delhi, 2020-09)
According to the World Health Organization report, around 10 million new cases are diagnosed with cancer in the year 2018 alone. Out of these, nearly 45% of the cancer incidences were reported from the Asian countries, 26% ...
Akhter, Sana; Raghava, Gajendra Pal Singh (Advisor)(IIIT-Delhi, 2019-06)
A significant burden of genetic disorders comes from the malfunctioning of the “suicide bags of the cells” called as the lysosomes and are referred to as Lysosomal Storage disorders or LSD’s. LSD’s comprises a major ...
Tumor development is rooted at genetic level with abnormalities in gene expressions as an important biomarker. Clear cell renal cell carcinoma, a histological subtype of Renal cell carcinoma is the one of the most common ...
A significant advancement in molecular biology has expanded the understanding of the biology of different diseases. However, these discoveries have not completely evolved into the precise treatment of the patient with ...
Shiju, S; Sriram, K (Advisor)(IIIT-Delhi, 2019-07)
Circadian rhythms (CR) are 24h endogenous oscillations seen in all organisms that control different biological processes including sleep-wake cycles, body temperature, cell division cycle, heartbeat, and metabolic rates. ...
With the escalation of medical/healthcare data, the need for automation has increased. The augmentation of automation desires newer and better technologies. SymEx, is one such tool that aims to parse the documents present ...
Khan, Biswadeep; Bera, Debajyoti (Advisor); Bagler, Ganesh (Advisor)(IIIT-Delhi, 2018-07)
Where does a particular food gets its flavor from? A food item is a complex combination of
(flavor) molecules, in different proportions, each having their own distinctive flavors. This
thesis takes a small step towards ...
Species evolve by adapting to variable thermal conditions. The differences in the thermal
stability of hyperthermophilic, thermophilic and mesophilic proteins arise partly due to their
structural variations. The goal of ...
Self-organized systems are known to be characterized with inherent complexity and hence are difficult to control. This complexity arises out of subtle interconnections among its subunits. Graph theory has emerged as a ...
Sepsis is one of biggest causes of mortality in patients admitted to the Intensive Care Units across the world. Its incidence in the developing countries including India is expected to be much higher than the developed ...
High-throughput technologies have revolutionized scientific research by producing copious amounts of data at a low cost. These large-scale biological data offers tremendous opportunities to understand the molecular mechanisms ...