Omic signatures of disease are important for personalized treatment because of theheterogeneity of diseases. Despite the advancement of computational tools, there arelimited methods that can capture the latent inter-relationships ...

The cryo-electron microscopy (cryo-EM) technique captures 2D projections of biological structures, revealing their inherent Heterogeneity arising from structural flexibility, conformational changes, and distinct functional ...

Detection of DNA base modifications Epigenetic modifications of DNA bases play an important role so, it’s important to detect the modifications in DNA. Hence, our goal is to detect and discover modifications in DNA and ...

Studying Chromatin Architecture is paramount to an understanding of cells or nuclei in disease and normal state. With recent advances in genomic technologies and computational power, new domains like Topologically associated ...

The RNA world is yet to be understood properly, and the same goes for repeat regions as there has been much research going on to understand their regulatory roles. Here, we have analyzed the RNA-DNA interaction and their ...

Recent development in the field of stem cell research field has evoked the great expectations. Researchers these days are full fledgedly working on developing methods to use self renewal potentials of stem cells in treating ...

Epigenetic memory is a vital cellular process. It regulates the inheritance of certain efficient traits of normal cells and the traits attained lately by the cells affected by diseases like Cancer from parents to daughter ...