Akanksha; Raghava, Gajendra Pal Singh (Advisor)(IIIT-Delhi, 2025-09)
Non-invasive diagnostics and therapeutics have the potential to revolutionize clinical practices by providing patient-friendly, accessible, and pain-free alternatives to traditional invasive methods. Among various biofluids, ...
G-protein-coupled receptors (GPCRs) are vital pharmaceutical targets, with more than one-third of FDA-approved drugs influencing their function. While central to cellular signaling and drug development, GPCR research is ...
CRISPR/Cas, a recently discovered genome-editing method depends on a single protein (Cas9) and non-coding RNA for gene-editing, which makes it simple, more rapid, versatile, efficient and manipulatable. Despite the ...
Understanding and predicting complex biological processes, from the interactions of molecules to the aging of cells, relies heavily on the ability to extract useful information from different types of biological data. ...
Cellular metabolites, traditionally seen as intermediates in metabolic pathways, perform diverse roles that extend into cellular signaling, homeostasis, and disease progression. This study deciphers the multifaceted roles ...
Cooking is a quintessential creative pursuit with profound significance for humanity. Food and cooking transcend mere sensory pleasure and have serious nutrition and public health outcomes. Beyond being linked to the ...
It is rare for individual genes to exert influence on biological processes in isolation. Instead, they are controlled by intricate networks of genes that collaborate in a well-organized manner. Complex biological processes ...
R Chandra, Omkar; Kumar, Vibhor (Advisor)(IIIT-Delhi, 2024-07-01)
There are thousands of genes with incomplete functional annotations, particularly non-coding genes. Understanding the functional roles of genes is crucial for dissecting the complex genomic regulatory mechanisms underlying ...
The escalating volume and intricate nature of healthcare and social care datasets necessitate the implementation of unconventional feature learning strategies to tackle current challenges. The examination of health and ...
Healthcare has been undergoing a data-driven transformation, further accelerated by the COVID-19 pandemic. A significant amount of healthcare data is unstructured and underutilized. The success of Large Language Models ...
Blood cancer has emerged as a growing concern over the past decade, necessitating early detection for timely and effective treatment. Traditional methods of diagnosing blood cancers involve a series of pathological tests ...
Cancer has become the second leading cause of mortality worldwide, and early de-tection and adequate treatment are crucial in reducing the cancer burden. Metastasis,which involves malignant cells detaching from the primary ...
Circadian rhythms (CR) are 24h endogenous oscillations seen in all organisms that control different biological processes including sleep-wake cycles, body temperature, cell division cycle, heartbeat, and metabolic rates. ...
Omic signatures of disease are important for personalized treatment because of theheterogeneity of diseases. Despite the advancement of computational tools, there arelimited methods that can capture the latent inter-relationships ...
Social determinants of health (SDOH) are the non-medical factors that play a vital role in public health and form the basis of health policies. Building an effective public health policy is a complex endeavor that ...
The advent of tissue and single cell based transcriptomic profiling technologies has allowed precise characterization of tissue specific gene activities in the context of development and disease. Human cells express about ...
For effective treatment regimens, decisions should be based on specific genetic variability present across different human body cells by taking advantage of already accessible large-scale omics data like genomics, epigenomics, ...
Single-cell transcriptomics is a powerful technique that has revolutionized our approach to dissect cellular phenotypes and diversity in complex tissues at an unprecedented res- olution. The emergence of this groundbreaking ...
Kaur, Dilraj; Raghava, Gajendra Pal Singh (Advisor)(IIIT-Delhi, 2022-06)
Innate immune system response is the initial/first line of defense against invading pathogens. It is non-specific and involves various cells like macrophages, neutrophils, natural killer cells, dendritic cells. The response ...
Lathwal, Anjali; Raghava, Gajendra Pal Singh (Advisor)(IIIT-Delhi, 2020-09)
According to the World Health Organization report, around 10 million new cases are diagnosed with cancer in the year 2018 alone. Out of these, nearly 45% of the cancer incidences were reported from the Asian countries, 26% ...