Detection of cancer for diagnosis and tracking the prognosis of the patients using liquid biopsy procedure: the extraction of blood for the detection of cells is the least invasive procedure and relatively fast process ...

Background: Studying Chromatin Architecture is paramount to an understanding of cells or nuclei in disease and normal state. With recent advances in genomic technologies and computational power, new domains like Topologically ...

BACE1 (beta-site amyloid precursor protein cleaving enzyme 1) is an aspartyl protease with a transmembrane domain that cleaves at the 671st position of amyloid precursor protein (APP) at the beta site. The production and ...

Due to the advent of next-generation sequencing techniques, the sequencing cost is reduced with increasing accuracy. We can use this as an advantage in liquid biopsy to identify and monitor cancer at different stages, which ...

Single cell RNA-seq data is an important source for profiling cellular heterogeneity. Clustering is an important step in any single cell pipeline because it allows us to discover unknown cell types.Furthermore,it is possible ...

Influenza A, an infectious viral disease affecting the lungs, is a significant public health concern. It has already caused four pandemics in the past, and some strains are now seasonal. Being zoonotic, the virus is ...

Recent development in the field of stem cell research field has evoked the great expectations. Researchers these days are full fledgedly working on developing methods to use self renewal potentials of stem cells in treating ...

The RNA world is yet to be understood properly, and the same goes for repeat regions as there has been much research going on to understand their regulatory roles. Here, we have analyzed the RNA-DNA interaction and their ...

Human cancers are composed of cells with varying genotypes, epigenetic states, and gene expression profiles. Intra and inter-tumor clonal heterogeneity is now recognized as one of the biggest drawbacks for therapeutic ...

Autism spectrum disorder (ASD) is a construct used to describes a cluster of behavioural features that span a range of issues, e.g., decreased social-emotional reciprocity and non-verbal communication in social interactions ...